Partners

Research collaborations

We are constantly working on publications with scientific researchers across the globe who use ALEX in their studies. As a science-oriented company, it is important to us to help further research in molecular diagnostics and allergology with the help of our patented allergy test. Currently, 35 studies are ongoing.

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Current research projects

Federal University of São Paulo, Brazil

Project lead: Dr. Lucila Camargo

Project topic: Banana allergy and peanut allergy

Project aim: To investigate the IgE profile of patients allergic to banana (and maybe other fruits) in São Paulo, as well as to investigate the IgE profile of patients allergic to peanut in Sao Paulo.

Expected results: To receive a better insight into the sensitisation patterns of the Brazilian population, especially on a molecular level. This will lead to an increased accuracy of allergy diagnosis in Brazil.

Contribution by MADx: To support this research effort, MADx provided ALEX² tests to Dr. Camargo and her team.

About Federal University of Sao Paulo

Medical University of Vienna, Austria

Project lead: Dr. Zsolt Szépfalusi

Project topic: IgE sensitisation profiles of school-aged children

Project aim: The objective of this project is to evaluate the IgE sensitisation profiles of school-aged children in an urban population in the capital of Austria/Vienna. The pediatric cohort has been recruited for a cross-sectional evaluation of SARS-CoV-2 prevalence in Austria during the early phases of pandemic in 2020.

Expected results: The evaluation of this population shall be used to establish the characterisation of an IgE antibody profile alongside a broad molecular signaling approach covered by the ALEX² Multiplex test.

Contribution by MADx: To support this research effort, MADx provided ALEX² tests to Dr. Szépfalusi and his team.

About Medical University Vienna

University of Pilsen, Czech Republic

Project lead: Dr. Martin Liška

Project topic: Legume allergy

Project aim: The aim of this project is to the IgE profile of legume-allergic patients with focus on pea and related legumes such as lentil, chickpea and beans.

Expected results: It is expected that specific IgE tests against relevant components of pea and related legumes will allow a better estimation of clinical relevance of sensitisation to these legumes.

Contribution by MADx: To support this research effort, MADx provided a customised array to Dr. Liška and his team.

About University of Pilsen

Completed research projects

Karl Landsteiner University of Health Sciences, Austria

Project lead: Tanja Kalic, PhD

Project topic: Fish allergy

Project aim: To investigate whether multiplex IgE testing reveals potentially tolerated fish through absence of IgE to parvalbumin and extracts from specific species.

Contribution by MADx: To support this research, MADx provided a research version of the ALEX² array to Tanja Kalic and her team.

About Karl Landsteiner University

University Hospital for Dermatology and Allergology of the Paracelsus Medical University Salzburg, Austria

Project lead: Assoc. - Prof. Mag. Dr. Roland Lang

Project topic: Comparison study of ALEX and ISAC

Project aim: The aim of this research was to perform a comprehensive comparison study between ALEX and ISAC.

Contribution by MADx: To support Prof. Lang’s study, MADx provided ALEX² arrays to Prof. Lang and his team.

About Paracelsus Medical University

What our research partners say

Project: Comparison ALEX & ISAC

or this study, we used patient sera from Northern Italy to perform an in-depth comparison between the two molecular allergy test systems ALEX and ISAC.

Project: Banana & peanut allergy

For our research, we are using the ALEX² test to investigate the IgE profile of patients in Sao Paulo allergic to bananas - and perhaps other fruits - as well as peanuts. This will give us better insight into sensitisation patterns of the Brazilian population at a molecular level to increase the accuracy of allergy diagnosis.

Project: IgE sensitisation profiles of school-aged children

In this project we are using the ALEX² test to evaluate the IgE profiles of school-aged children in Vienna during the SARS-CoV-2 pandemic in 2020. We expect to characterise an IgE antibody profile and a broad molecular signaling approach covered by ALEX².

Project: Legume allergy

We are currently working on a project regarding the IgE profiles of legume-allergic patients. MADx is supporting our research by providing a customised array for this purpose. We hope that the results will point to IgE tests allowing for a better estimation of clinical relevance of sensitisation to legumes such as lentil, chickpea and beans.

Project: Fish allergy

We tested sera from fish-allergic patients in Austria, China, Denmark, Luxembourg, Norway, and Spain for specific IgE to parvalbumins and extracts from 10 different fish species. We were able to determine that parvalbumins and extracts from several species should be added to the routine diagnostic panels. This approach could help identify which species can be tolerated by the individual patients.

Publications

Making our research visible: We are taking over scientific resonsibility and are constantly working on new publications.